Pdr drug summaries are concise pointofcare prescribing, dosing and administering information to help phsyicans more efficiently and accurately prescribe in their practice pdr s drug summaries are available free of charge and serve as a great resource for us based mds, dos, nps and pas in patient practice. One reagent lane fair lawn, nj 07410 for information in north america, call. N dot marine pollutant n dot severe marine pollutant n. This material is considered hazardous by the osha hazard communication standard 29 cfr 1910.
Aspirin is only found in individuals who have consumed this drug. Department of transportation reportable quantity rq. Your new online msds binder is a place for you to store the material safety data sheets you need to deploy. Acetylsalicylic acid not listed as a carcinogen by acgih, iarc, ntp, or ca prop 65. Immediately flush eyes with excess water for 15 minutes, lifting lower and upper eyelids occasionally. Safety data sheet chandlergilbert community college. Solubility of acetylsalicylic acid in ethanol, acetone. Aspirin, also known as acetylsalicylic acid asa, is a medication used to reduce pain, fever, or inflammation. The information in cameo chemicals comes from a variety of data sources. See actual entry in rtecs for complete information. Aspirin material safety data sheet cas no 50782 sdsmsds. Material safety data sheet page 1 of 2 acetylsalicylic acid. Page 6 of 8 msds acetic acid photo chemically produced hydroxyl radicals. Ecotrin aspirin dose, indications, adverse effects.
A meta description is an html tag in the html code of your website, which allows you to customize a section of text that describes the page itself. Hold eyelids apart and flush eyes with plenty of water for at least 15 minutes. Specific inflammatory conditions which aspirin is used to treat include kawasaki disease, pericarditis, and rheumatic fever. Other references state that a 10 g dose 143 mgkg may be fatal in humans. Excerpt from erg guide 154 substances toxic andor corrosive noncombustible. As the reaction proceeds, the solid salicylic acid disappears and the acetylsalicylic acid product. Acetylsalicylic acid aspirin not listed not listed ec50 360 mgl 1 h ec50 900 mgl 1 h ec50. State righttoknow regulations component massachusettsnew jersey pennsylvania illinois rhode island acetylsalicylic acid aspirin x x x u.
Slightly hazardous in case of skin contact corrosive. Nov 14, 2007 as one of the most regularly tradedin medicines in the world, acetylsalicylic acid has been scarcely researched when in solution. Acetylsalicylic acid is slightly soluble in water, with a limit of solubility reported as approximately 3 mgml at 25 deg c. It results from the elimination of a molecule of water from two molecules of acetic acid see fig.
Keep container tightly closed do not eat, drink or smoke when using this product wash skin thoroughly after handling. Material safety data sheet anokaramsey community college. Dissolve or mix the material with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber. In this lab, students will analyze aspirin acetylsalicylic acid tablets for the acetylsalicylic acid content, using a volumetric analysis technique called titration. This study is aimed at determining the solubility of acetylsalicylic acid in ethanol, acetone, propylene glycol, and 2propanol, in addition to comparing their solubility values with the expected from an ideal solution. O acetylsalicylic acid 2acetoxybenzoic acid aspirin formula. Contact a licensed professional waste disposal service to dispose of this material. First aid measures always seek professional medical attention after first aid measures are provided.
Hazardous decomposition products formed under fire conditions. Hazards identification potential acute health effects. This chemical is considered hazardous according to the 2012 osha hazard communication. Oacetylsalicylic acid 2acetoxybenzoic acid aspirin formula. This product contains acetylsalicylic acid aspirin, a.
Acetylsalicylic acid aspirin 50782 ec50 360 mgl 1 h ec50 900 mgl 1 h 48h ec50. Aqueous solutions of acetylsalicylic acid are most stable at ph 2 3, but to assure full. As an immediate precautionary measure, isolate spill or leak area in all directions for at least 50 meters 150 feet for liquids and at least 25 meters 75 feet for solids. Synthesis of acetylsalicylic acid essay free essays, term. Sigmaaldrich offers a number of acetylsalicylic acid products. Rat 340 mgkgoacetylsalicylic acid skin corrosionirritation skin rabbitoacetylsalicylic acid result. No skin irritation serious eye damageeye irritation eyes rabbitoacetylsalicylic. Acetylsalicylic acid an overview sciencedirect topics. Safety data sheet northwest missouri state university. Bioaccumulation accumulationno information available. Apr 12, 2020 acetylsalicylic acid asa is better known to most people by its common name, aspirin. Ac158180000, ac158180500, ac158185000, ac385760000 synonyms. In the us, acetylsalicylic acid is a member of the following drug classes.
Hazardous in case of skin contact irritant, of eye contact irritant. National library of medicine hazardous substances data bank online. It is also soluble in ethanol at 50 mgml and will dissolve in solutions of alkali hydroxides and carbonates with decomposition. Acetic acid, glacial alcohol of vinegar carboxylic acid c2 ethanoic acid ethylic acid methanecarboxylic acid pyroligneous acid vinegar acid 1. Our msds database is an easy to use, do it yourself tool, and best of all. Not all of the mass of an aspirin tablet is acetylsalicylic acid, as there are starch binders added to hold the tablet together. California, new jersey, florida, pennsylvania, minnesota, massachusetts. Material safety data sheet acetylsalicylic acid product observe all federal, state, and local environmental regulations. Strong oxidizing agents, strong reducing agents, bases, alcohols, metal.
Acetylsalicylic acid 50782 100 toxicological data on ingredients. Physical and chemical properties molecular formula c9h8o4. Oral, category 4 skin corrosionirritation, category 3. Sulfuric acid, acs safety data sheet according to federal register vol. As one of the most regularly tradedin medicines in the world, acetylsalicylic acid has been scarcely researched when in solution. Synthesis of acetylsalicylic acid topics, sample papers. Hazardous to health regulations coshh 2002 as amended. The balanced chemical reaction of the formation of aspirin. Safety data sheet according to 29cfr19101200 and ghs rev. Bioaccumulation no information available chemical name log pow acetylsalicylic acid aspirin 50782 1. This product contains the following ingredients for which the state of california has found to cause reproductive harm male which would require a warning under the statute. Precautionary statements p261 avoid breathing dust. Slightly hazardous in case of skin contact corrosive, permeator, of ingestion, of. Ignition sources, contact with water, excess heat, exposure to moist air or water.
Product and company identification acetylsalicylic acid. This study is aimed at determining the solubility of acetylsalicylic acid in ethanol, acetone, propylene glycol, and 2propanol, in addition to comparing their solubility values with the expected. It plays a role in how your page is seen by search engine crawlers, and how it appears in serps. Most important symptoms and effects, both acute and delayed. Acetylsalicylic acid is prepared by reacting acetic anhydride with salicylic acid at a temperature of acetic acid or aromatic, acyclic, or chlorinated hydrocarbons or by the addition of catalysts such as acids or tertiary amines. Identification of the substancemixture and of the companyundertaking 1. Other information prepared by regulatory affairs thermo fisher scientific email. The following statements isare made in order to comply with the california safe drinking water act. Acetylsalicylic acid aspirin can be found on the following state right to know lists. Novacyl safety data sheet for rhodine 3020, version 11, 20 february 2014. Acetylsalicylic acid aspirin 50782 developmental female reproductive developmental u.
Will likely be mobile in the environment due to its water solubility. The hazard fields include special hazard alerts air and water reactions, fire hazards, health hazards, a reactivity profile, and details about reactive groups assignments and potentially incompatible absorbents. The following statements isare made in order to comply with. Seek medical attention if irritation, discomfort, or vomiting persists. Aspirin is an orally administered nonsteroidal antiinflammatory agent. Acetylsalicylic acid get uptodate information on acetylsalicylic acid side effects, uses, dosage, overdose, pregnancy, alcohol and more. Other companies are charging thousands of dollars to set up accounts and give you access to their msds online database.
Wear appropriate protective eyeglasses or chemical safety goggles as described by oshas eye and face protection regulations in 29 cfr 1910. First aid measures description of first aid measures. Aspirin or acetylsalicylic acid acetosal is a drug in the family of salicylates, often used as an analgesic against minor pains and aches, antipyretic against fever, and antiinflammatory. Acetylsalicylic acid binds to and acetylates serine residues in cyclooxygenases, resulting in decreased synthesis of prostaglandin, platelet aggregation, and inflammation. When released into air, this material is expected to have a halflife between 10 and 30 days. A combination of sodium salicylate and acetyl chloride, this medication is the first nonsteroidal antiinflammatory drug to be developed, and its been in use for over a century. This product contains acetylsalicylic acid, a chemical known.
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